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A Meta-analysis of Pricking Blood Therapy combined with Acupuncture in the Treatment of Knee OsteoarthritisCN

FAN Si-qi;ZENG Ping;LIU Xiong;CHEN Jin-long;NONG Jiao;The Postgraduate College of Guangxi University of Chinese Medicine;The First Affiliated Hospital of Guangxi University of Chinese Medicine;

Abstract:Objective: To systematic review of the efficacy of pricking blood therapy combined with acupuncture in the treatment of knee osteoarthritis(KAO). Methods: The literatures on clinical randomized controlled trials of pricking blood therapy for KAO in CNKI, Wanfang database, VIP database, Pubmed database and CBM were searched by computer. The original literatures were screened according to the proposed inclusion and exclusion criteria, and the quality of the literatures was evaluated and Meta-analyzed. Review Manager 5.3 software was used to test the heterogeneity and calculate the OR value and 95% confidence interval of each index. Results: 10 articles were included in the study, 3 of them were high quality research and 7 were low quality research. The cure rate and the total effective rate of OR and 95% CI were: the total effective rate was[OR=4.38, 95%CI(2.63,7.28), P<0.00001], the cure rate was [OR=2.40, 95%CI(1.54, 3.74), P=0.0001]. Among them,there were 577 samples with VAS score as pain index, and the combined effect of mean deviation(MD) of VAS difference before and after treatment was [MD =-1.81, 95% CI(-2.33,-1.28), P <0.000,01], which indicated that pricking blood therapy combined with acupuncture treatment of KOA is better than conventional acupuncture or simple western medicine treatment. Conclusion: Pricking blood therapy combined with acupuncture has more advantages in the treatment of KOA than conventional acupuncture or western medicine alone. Due to the low quality, small sample size and possible bias of the included studies, more randomized controlled studies with high quality and standardized methodology are needed.
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  • Series:

    (E) Medicine & Public Health

  • Subject:

    Traditional Chinese Medicine

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